CBD AND ADDICTION
Cannabidiol Improves Cognitive Impairment and
Reverses Cortical Transcriptional Changes Induced by Ketamine, in
Schizophrenia-Like Model in Rats.
Kozela E, Krawczyk M, Kos T, Juknat A, Vogel Z, Popik P.
Mol Neurobiol. 2019 Dec 11. doi: 10.1007/s12035-019-01831-2. [Epub
ahead of print] PMID:31823199
Effects of cannabidiol (CBD) in neuropsychiatric
disorders: A review of pre-clinical and clinical findings.
Elsaid S, Kloiber S, Le Foll B.
Prog Mol Biol Transl Sci. 2019;167:25-75. doi:
10.1016/bs.pmbts.2019.06.005. Epub 2019 Aug 28. PMID:31601406
Cannabidiol Counteracts the Psychotropic
Side-Effects of Δ-9-Tetrahydrocannabinol in the Ventral
Hippocampus through Bidirectional Control of ERK1-2
Phosphorylation.
Hudson R, Renard J, Norris C, Rushlow WJ, Laviolette SR.
J Neurosci. 2019 Oct 30;39(44):8762-8777. doi:
10.1523/JNEUROSCI.0708-19.2019. Epub 2019 Sep 30. PMID:31570536
Clinicians' Guide to Cannabidiol and
Hemp Oils.
VanDolah HJ, Bauer BA, Mauck KF.
Mayo Clin Proc. 2019 Sep;94(9):1840-1851. doi:
10.1016/j.mayocp.2019.01.003. Epub 2019 Aug 22. Review.
PMID:31447137
Free Article
Cannabidiol attenuates the rewarding effects of
cocaine in rats by CB2, 5-TH1A and TRPV1 receptor
mechanisms.
Galaj E, Bi GH, Yang HJ, Xi ZX.
Neuropharmacology. 2019 Aug 19:107740. doi:
10.1016/j.neuropharm.2019.107740. [Epub ahead of print]
PMID:31437433
Cannabis Use and Cognition in Adults Prescribed
Opioids for Persistent Pain.
Wildes M, Bigand TL, Layton ME, Wilson M.
Pain Manag Nurs. 2020 Feb;21(1):94-99. doi:
10.1016/j.pmn.2019.06.014. Epub 2019 Aug 9. PMID:31405787
The Potential of Cannabidiol as a Treatment for
Psychosis and Addiction: Who Benefits Most? A Systematic Review.
Batalla A, Janssen H, Gangadin SS, Bossong MG.
J Clin Med. 2019 Jul 19;8(7). pii: E1058. doi: 10.3390/jcm8071058.
Review. PMID:31330972
Free PMC Article
Cannabidiol Treatment Might Promote Resilience to
Cocaine and Methamphetamine Use Disorders: A Review of Possible
Mechanisms.
Calpe-López C, García-Pardo MP, Aguilar MA.
Molecules. 2019 Jul 16;24(14). pii: E2583. doi:
10.3390/molecules24142583. Review. PMID:31315244
Free PMC Article
Cannabidiol inhibits sucrose self-administration
by CB1 and CB2 receptor mechanisms in rodents.
Bi GH, Galaj E, He Y, Xi ZX.
Addict Biol. 2019 Jun 19:e12783. doi: 10.1111/adb.12783. [Epub ahead
of print] PMID:31215752
Therapeutic Prospects of Cannabidiol for Alcohol
Use Disorder and Alcohol-Related Damages on the Liver and the
Brain.
De Ternay J, Naassila M, Nourredine M, Louvet A, Bailly F, Sescousse
G, Maurage P, Cottencin O, Carrieri PM, Rolland B.
Front Pharmacol. 2019 May 31;10:627. doi: 10.3389/fphar.2019.00627.
eCollection 2019. Review. PMID:31214036
Free PMC Article
Effects of cannabidiol on alcohol-related
outcomes: A review of preclinical and human research.
Nona CN, Hendershot CS, Le Foll B.
Exp Clin Psychopharmacol. 2019 Aug;27(4):359-369. doi:
10.1037/pha0000272. Epub 2019 May 23. Review. PMID:31120285
Cannabidiol for the Reduction of Cue-Induced
Craving and Anxiety in Drug-Abstinent Individuals With Heroin Use
Disorder: A Double-Blind Randomized Placebo-Controlled Trial.
Hurd YL, Spriggs S, Alishayev J, Winkel G, Gurgov K, Kudrich C,
Oprescu AM, Salsitz E.
Am J Psychiatry. 2019 Nov 1;176(11):911-922. doi:
10.1176/appi.ajp.2019.18101191. Epub 2019 May 21. PMID:31109198
Gender differences in the effects of cannabidiol
on ethanol binge drinking in mice.
Viudez-Martínez A, García-Gutiérrez MS, Manzanares J.
Addict Biol. 2019 May 9:e12765. doi: 10.1111/adb.12765. [Epub ahead
of print] PMID:31074060
Acute effects of cannabinoids on addiction
endophenotypes are moderated by genes encoding the CB1 receptor
and FAAH enzyme.
Hindocha C, Freeman TP, Schafer G, Gardner C, Bloomfield MAP, Bramon
E, Morgan CJA, Curran HV.
Addict Biol. 2019 Apr 23:e12762. doi: 10.1111/adb.12762. [Epub ahead
of print] PMID:31013550
The Endocannabinoid System and Cannabidiol's
Promise for the Treatment of Substance Use Disorder.
Chye Y, Christensen E, Solowij N, Yücel M.
Front Psychiatry. 2019 Feb 19;10:63. doi: 10.3389/fpsyt.2019.00063.
eCollection 2019. Review. PMID:30837904
Free PMC Article Cannabidiol modulates the expression of
neuroinflammatory factors in stress- and drug-induced
reinstatement of methamphetamine in extinguished rats.
Karimi-Haghighi S, Dargahi L, Haghparast A.
Addict Biol. 2019 Feb 22. doi: 10.1111/adb.12740. [Epub ahead of
print] PMID:30793820
Cannabidiol as a Novel Candidate Alcohol Use
Disorder Pharmacotherapy: A Systematic Review.
Turna J, Syan SK, Frey BN, Rush B, Costello MJ, Weiss M, MacKillop
J.
Alcohol Clin Exp Res. 2019 Apr;43(4):550-563. doi:
10.1111/acer.13964. Epub 2019 Feb 19. Review. PMID:30698831
Repeated Cannabidiol treatment reduces cocaine
intake and modulates neural proliferation and CB1R expression in
the mouse hippocampus.
Luján MÁ, Castro-Zavala A, Alegre-Zurano L, Valverde O.
Neuropharmacology. 2018 Dec;143:163-175. doi:
10.1016/j.neuropharm.2018.09.043. Epub 2018 Sep 28. PMID:30273593
Individual and combined effects of acute
delta-9-tetrahydrocannabinol and cannabidiol on psychotomimetic
symptoms and memory function.
Morgan CJA, Freeman TP, Hindocha C, Schafer G, Gardner C, Curran HV.
Transl Psychiatry. 2018 Sep 5;8(1):181. doi:
10.1038/s41398-018-0191-x. PMID:30185793
Free PMC Article
A Model of Δ9-Tetrahydrocannabinol
Self-administration and Reinstatement That Alters Synaptic
Plasticity in Nucleus Accumbens.
Spencer S, Neuhofer D, Chioma VC, Garcia-Keller C, Schwartz DJ,
Allen N, Scofield MD, Ortiz-Ithier T, Kalivas PW.
Biol Psychiatry. 2018 Oct 15;84(8):601-610. doi:
10.1016/j.biopsych.2018.04.016. Epub 2018 May 3. Erratum in: Biol Psychiatry. 2019 May 15;85(10):881.
PMID:29861097
Free PMC Article
Review of the neurological benefits of
phytocannabinoids.
Maroon J, Bost J.
Surg Neurol Int. 2018 Apr 26;9:91. doi: 10.4103/sni.sni_45_18.
eCollection 2018. Review. PMID:29770251
Free PMC Article
The effects of cannabidiol on impulsivity and
memory during abstinence in cigarette dependent smokers.
Hindocha C, Freeman TP, Grabski M, Crudgington H, Davies AC, Stroud
JB, Das RK, Lawn W, Morgan CJA, Curran HV.
Sci Rep. 2018 May 15;8(1):7568. doi: 10.1038/s41598-018-25846-2.
PMID:29765102
Free PMC Article
Cannabidiol reverses attentional bias to cigarette
cues in a human experimental model of tobacco withdrawal.
Hindocha C, Freeman TP, Grabski M, Stroud JB, Crudgington H, Davies
AC, Das RK, Lawn W, Morgan CJA, Curran HV.
Addiction. 2018 May 1. doi: 10.1111/add.14243. [Epub ahead of print]
PMID:29714034
Free PMC Article
Unique treatment potential of cannabidiol for the
prevention of relapse to drug use: preclinical proof of principle.
Gonzalez-Cuevas G, Martin-Fardon R, Kerr TM, Stouffer DG, Parsons
LH, Hammell DC, Banks SL, Stinchcomb AL, Weiss F.
Neuropsychopharmacology. 2018 Sep;43(10):2036-2045. doi:
10.1038/s41386-018-0050-8. Epub 2018 Mar 22. PMID:29686308
Free PMC Article
Nabiximols combined with motivational
enhancement/cognitive behavioral therapy for the treatment of
cannabis dependence: A pilot randomized clinical trial.
Trigo JM, Soliman A, Quilty LC, Fischer B, Rehm J, Selby P, Barnes
AJ, Huestis MA, George TP, Streiner DL, Staios G, Le Foll B.
PLoS One. 2018 Jan 31;13(1):e0190768. doi:
10.1371/journal.pone.0190768. eCollection 2018. PMID:29385147
Free PMC Article
Modulation of Astrocyte Activity by Cannabidiol, a
Nonpsychoactive Cannabinoid.
Kozela E, Juknat A, Vogel Z.
Int J Mol Sci. 2017 Jul 31;18(8). pii: E1669. doi:
10.3390/ijms18081669. Review. PMID:28788104
Free PMC Article
Cannabis: An Overview of its Adverse Acute and
Chronic Effects and its Implications. Ford TC, Hayley AC,
Downey LA, Parrott AC.
Curr Drug Abuse Rev. 2017;10(1):6-18. doi:
10.2174/1874473710666170712113042. Review. PMID:28707583
Cannabidiol reduces ethanol consumption,
motivation and relapse in mice.
Viudez-Martínez A, García-Gutiérrez MS, Navarrón CM,
Morales-Calero MI, Navarrete F, Torres-Suárez AI, Manzanares J.
Addict Biol. 2018 Jan;23(1):154-164. doi: 10.1111/adb.12495. Epub
2017 Feb 13. PMID:28194850
Is there a role for cannabidiol in psychiatry?
Khoury JM, Neves MCLD, Roque MAV, Queiroz DAB, Corrêa de Freitas
AA, de Fátima Â, Moreira FA, Garcia FD.
World J Biol Psychiatry. 2019 Feb;20(2):101-116. doi:
10.1080/15622975.2017.1285049. Epub 2017 Feb 20. PMID:28112021
Pharmacokinetic Drug Interactions with Tobacco,
Cannabinoids and Smoking Cessation Products.
Anderson GD, Chan LN.
Clin Pharmacokinet. 2016 Nov;55(11):1353-1368. Review. PMID:27106177
Pathways and gene networks mediating the
regulatory effects of cannabidiol, a nonpsychoactive cannabinoid,
in autoimmune T cells.
Kozela E, Juknat A, Gao F, Kaushansky N, Coppola G, Vogel Z.
J Neuroinflammation. 2016 Jun 3;13(1):136. doi:
10.1186/s12974-016-0603-x. PMID:27256343
Free PMC Article
Cannabidiol Counteracts Amphetamine-Induced
Neuronal and Behavioral Sensitization of the Mesolimbic Dopamine
Pathway through a Novel mTOR/p70S6 Kinase Signaling Pathway.
Renard J, Loureiro M, Rosen LG, Zunder J, de Oliveira C, Schmid S,
Rushlow WJ, Laviolette SR.
J Neurosci. 2016 May 4;36(18):5160-9. doi:
10.1523/JNEUROSCI.3387-15.2016. PMID:27147666
Free PMC Article
Effects of fixed or self-titrated dosages of
Sativex on cannabis withdrawal and cravings. Trigo JM,
Lagzdins D, Rehm J, Selby P, Gamaleddin I, Fischer B, Barnes AJ,
Huestis MA, Le Foll B.
Drug Alcohol Depend. 2016 Apr 1;161:298-306. doi:
10.1016/j.drugalcdep.2016.02.020. Epub 2016 Feb 23. PMID:26925704
Free PMC Article
THC:CBD in Daily Practice: Available Data from UK,
Germany and Spain.
Fernández Ó.
Eur Neurol. 2016;75 Suppl 1:1-3. doi: 10.1159/000444234. Epub 2016
Feb 23. Review. PMID:26901342
Free Article
Cannabidiol disrupts the reconsolidation of
contextual drug-associated memories in Wistar rats.
de Carvalho CR, Takahashi RN.
Addict Biol. 2017 May;22(3):742-751. doi: 10.1111/adb.12366. Epub
2016 Feb 1. PMID:26833888
Cannabidiol Oil for Decreasing Addictive Use of
Marijuana: A Case Report.
Shannon S, Opila-Lehman J.
Integr Med (Encinitas). 2015 Dec;14(6):31-5. PMID:26807069
Free PMC Article
Early Phase in the Development of Cannabidiol as a
Treatment for Addiction: Opioid Relapse Takes Initial Center
Stage.
Hurd YL, Yoon M, Manini AF, Hernandez S, Olmedo R, Ostman M,
Jutras-Aswad D.
Neurotherapeutics. 2015 Oct;12(4):807-15. doi:
10.1007/s13311-015-0373-7. Review. PMID:26269227
Free PMC Article
Cannabidiol as an Intervention for Addictive
Behaviors: A Systematic Review of the Evidence.
Prud'homme M, Cata R, Jutras-Aswad D.
Subst Abuse. 2015 May 21;9:33-8. doi: 10.4137/SART.S25081.
eCollection 2015. Review. PMID:26056464
Free PMC Article
Safety and pharmacokinetics of oral cannabidiol
when administered concomitantly with intravenous fentanyl in
humans.
Manini AF, Yiannoulos G, Bergamaschi MM, Hernandez S, Olmedo R,
Barnes AJ, Winkel G, Sinha R, Jutras-Aswad D, Huestis MA, Hurd YL.
J Addict Med. 2015 May-Jun;9(3):204-10. doi:
10.1097/ADM.0000000000000118. PMID:25748562
Free PMC Article
Cannabidiol reduces cigarette consumption in
tobacco smokers: preliminary findings. Morgan CJ, Das RK, Joye
A, Curran HV, Kamboj SK.
Addict Behav. 2013 Sep;38(9):2433-6. doi:
10.1016/j.addbeh.2013.03.011. Epub 2013 Apr 1. PMID:23685330