CBD AND CANCER

[Cannabidiol in cancer treatment].
Likar R, Köstenberger M, Nahler G.
Schmerz. 2020 Jan 2. doi: 10.1007/s00482-019-00438-9. [Epub ahead of print] Review. German.
PMID:31897700

Potential role of cannabidiol for seizure control in a patient with recurrent glioma.
Hsu K, Whitham E, Kichenadasse G.
J Clin Neurosci. 2019 Dec 14. pii: S0967-5868(19)31306-2. doi: 10.1016/j.jocn.2019.11.024. [Epub ahead of print]
PMID:31848037

CBD loaded microparticles as a potential formulation to improve paclitaxel and doxorubicin-based chemotherapy in breast cancer.
Fraguas-Sánchez AI, Fernández-Carballido A, Simancas-Herbada R, Martin-Sabroso C, Torres-Suárez AI.
Int J Pharm. 2020 Jan 25;574:118916. doi: 10.1016/j.ijpharm.2019.118916. Epub 2019 Dec 4.
PMID:31811927

Cannabidiol promotes apoptosis via regulation of XIAP/Smac in gastric cancer.
Jeong S, Jo MJ, Yun HK, Kim DY, Kim BR, Kim JL, Park SH, Na YJ, Jeong YA, Kim BG, Ashktorab H, Smoot DT, Heo JY, Han J, Il Lee S, Do Kim H, Kim DH, Oh SC, Lee DH.
Cell Death Dis. 2019 Nov 7;10(11):846. doi: 10.1038/s41419-019-2001-7.
PMID:31699976

Free PMC Article Concomitant Treatment of Malignant Brain Tumours With CBD - A Case Series and Review of the Literature.
Likar R, Koestenberger M, Stultschnig M, Nahler G.
Anticancer Res. 2019 Oct;39(10):5797-5801. doi: 10.21873/anticanres.13783.
PMID:31570484

[Efficacy and safety of medicinal cannabis: results of the CaPRis study].
Hoch E, Friemel C, Schneider M, Pogarell O, Hasan A, Preuss UW; CaPRis-Projektgruppe.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2019 Jul;62(7):825-829. doi: 10.1007/s00103-019-02965-3. Review. German.
PMID:31214723

Dramatic response to Laetrile and cannabidiol (CBD) oil in a patient with metastatic low grade serous ovarian carcinoma.
Barrie AM, Gushue AC, Eskander RN.
Gynecol Oncol Rep. 2019 May 17;29:10-12. doi: 10.1016/j.gore.2019.05.004. eCollection 2019 Aug.
PMID:31193514

Free PMC Article Future Aspects for Cannabinoids in Breast Cancer Therapy.
Kisková T, Mungenast F, Suváková M, Jäger W, Thalhammer T.
Int J Mol Sci. 2019 Apr 3;20(7). pii: E1673. doi: 10.3390/ijms20071673. Review.
PMID:30987191

Free PMC Article Role of miRNA in the regulation of cannabidiol-mediated apoptosis in neuroblastoma cells.
Alharris E, Singh NP, Nagarkatti PS, Nagarkatti M.
Oncotarget. 2019 Jan 1;10(1):45-59. doi: 10.18632/oncotarget.26534. eCollection 2019 Jan 1.
PMID:30713602

Free PMC Article Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer.
Sharafi G, He H, Nikfarjam M.
J Pancreat Cancer. 2019 Jan 25;5(1):1-7. doi: 10.1089/pancan.2018.0019. eCollection 2019. Review.
PMID:30706048

Free PMC Article Cannabinoids as a Potential New and Novel Treatment for Melanoma: A Pilot Study in a Murine Model.
Simmerman E, Qin X, Yu JC, Baban B.
J Surg Res. 2019 Mar;235:210-215. doi: 10.1016/j.jss.2018.08.055. Epub 2018 Oct 30.
PMID:30691796

Cannabidiol modulates phosphorylated rpS6 signalling in a zebrafish model of Tuberous Sclerosis Complex.
Serra I, Scheldeman C, Bazelot M, Whalley BJ, Dallas ML, de Witte PAM, Williams CM.
Behav Brain Res. 2019 May 2;363:135-144. doi: 10.1016/j.bbr.2019.01.040. Epub 2019 Jan 23.
PMID:30684511

Cannabidiol-induced apoptosis is mediated by activation of Noxa in human colorectal cancer cells.
Jeong S, Yun HK, Jeong YA, Jo MJ, Kang SH, Kim JL, Kim DY, Park SH, Kim BR, Na YJ, Lee SI, Kim HD, Kim DH, Oh SC, Lee DH.
Cancer Lett. 2019 Apr 10;447:12-23. doi: 10.1016/j.canlet.2019.01.011. Epub 2019 Jan 18.
PMID:30660647

Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and Reduces Prohibitin Protein in Glioblastoma Multiforme Cells.
Kosgodage US, Uysal-Onganer P, MacLatchy A, Mould R, Nunn AV, Guy GW, Kraev I, Chatterton NP, Thomas EL, Inal JM, Bell JD, Lange S.
Transl Oncol. 2019 Mar;12(3):513-522. doi: 10.1016/j.tranon.2018.12.004. Epub 2018 Dec 28.
PMID:30597288

Free PMC Article Lipid nanocapsules decorated and loaded with cannabidiol as targeted prolonged release carriers for glioma therapy: In vitro screening of critical parameters. Aparicio-Blanco J, Sebastián V, Benoit JP, Torres-Suárez AI.
Eur J Pharm Biopharm. 2019 Jan;134:126-137. doi: 10.1016/j.ejpb.2018.11.020. Epub 2018 Nov 22.
PMID:30472144

Oral cannabinoid-rich THC/CBD cannabis extract for secondary prevention of chemotherapy-induced nausea and vomiting: a study protocol for a pilot and definitive randomised double-blind placebo-controlled trial (CannabisCINV).
Mersiades AJ, Tognela A, Haber PS, Stockler M, Lintzeris N, Simes J, McGregor I, Olver I, Allsop DJ, Gedye C, Kirby AC, Morton RL, Fox P, Clarke S, Briscoe K, Aghmesheh M, Wong N, Walsh A, Hahn C, Grimison P.
BMJ Open. 2018 Sep 12;8(9):e020745. doi: 10.1136/bmjopen-2017-020745.
PMID:30209152

Free PMC Article Targeting Glioma Initiating Cells with A combined therapy of cannabinoids and temozolomide.
López-Valero I, Saiz-Ladera C, Torres S, Hernández-Tiedra S, García-Taboada E, Rodríguez-Fornés F, Barba M, Dávila D, Salvador-Tormo N, Guzmán M, Sepúlveda JM, Sánchez-Gómez P, Lorente M, Velasco G.
Biochem Pharmacol. 2018 Nov;157:266-274. doi: 10.1016/j.bcp.2018.09.007. Epub 2018 Sep 7.
PMID:30195736

Free Article Optimization of a preclinical therapy of cannabinoids in combination with temozolomide against glioma.
López-Valero I, Torres S, Salazar-Roa M, García-Taboada E, Hernández-Tiedra S, Guzmán M, Sepúlveda JM, Velasco G, Lorente M.
Biochem Pharmacol. 2018 Nov;157:275-284. doi: 10.1016/j.bcp.2018.08.023. Epub 2018 Aug 18.
PMID:30125556

GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine. Ferro R, Adamska A, Lattanzio R, Mavrommati I, Edling CE, Arifin SA, Fyffe CA, Sala G, Sacchetto L, Chiorino G, De Laurenzi V, Piantelli M, Sansom OJ, Maffucci T, Falasca M.
Oncogene. 2018 Dec;37(49):6368-6382. doi: 10.1038/s41388-018-0390-1. Epub 2018 Jul 30.
PMID:30061636

Novel mechanism of cannabidiol-induced apoptosis in breast cancer cell lines.
Sultan AS, Marie MA, Sheweita SA.
Breast. 2018 Oct;41:34-41. doi: 10.1016/j.breast.2018.06.009. Epub 2018 Jun 22.
PMID:30007266

CBD: a biomarker database for colorectal cancer.
Zhang X, Sun XF, Cao Y, Ye B, Peng Q, Liu X, Shen B, Zhang H.
Database (Oxford). 2018 Jan 1;2018. doi: 10.1093/database/bay046.
PMID:29846545

Free PMC Article The current state and future perspectives of cannabinoids in cancer biology.
Śledziński P, Zeyland J, Słomski R, Nowak A.
Cancer Med. 2018 Mar;7(3):765-775. doi: 10.1002/cam4.1312. Epub 2018 Feb 23. Review. Erratum in: Cancer Med. 2018 Nov;7(11):5859.
PMID:29473338

Free PMC Article Cannabinoid-induced cell death in endometrial cancer cells: involvement of TRPV1 receptors in apoptosis.
Fonseca BM, Correia-da-Silva G, Teixeira NA.
J Physiol Biochem. 2018 May;74(2):261-272. doi: 10.1007/s13105-018-0611-7. Epub 2018 Feb 13.
PMID:29441458

Cynanbungeigenin C and D, a pair of novel epimers from Cynanchum bungei, suppress hedgehog pathway-dependent medulloblastoma by blocking signaling at the level of Gli.
Li XY, Zhou LF, Gao LJ, Wei Y, Xu SF, Chen FY, Huang WJ, Tan WF, Ye YP.
Cancer Lett. 2018 Apr 28;420:195-207. doi: 10.1016/j.canlet.2018.02.005. Epub 2018 Feb 6.
PMID:29425683

The use of cannabidiol for seizure management in patients with brain tumor-related epilepsy.
Warren PP, Bebin EM, Nabors LB, Szaflarski JP.
Neurocase. 2017 Oct - Dec;23(5-6):287-291. doi: 10.1080/13554794.2017.1391294. Epub 2017 Oct 24.
PMID:29063814

Cannabidiol and palmitoylethanolamide are anti-inflammatory in the acutely inflamed human colon.
Couch DG, Tasker C, Theophilidou E, Lund JN, O'Sullivan SE.
Clin Sci (Lond). 2017 Oct 25;131(21):2611-2626. doi: 10.1042/CS20171288. Print 2017 Nov 1.
PMID:28954820

The use of cannabis in supportive care and treatment of brain tumor.
Likar R, Nahler G.
Neurooncol Pract. 2017 Sep;4(3):151-160. doi: 10.1093/nop/npw027. Epub 2017 Jan 18. Review.
PMID:31385997

Free PMC Article Anticancer effects of phytocannabinoids used with chemotherapy in leukaemia cells can be improved by altering the sequence of their administration.
Scott KA, Dalgleish AG, Liu WM.
Int J Oncol. 2017 Jul;51(1):369-377. doi: 10.3892/ijo.2017.4022. Epub 2017 May 29.
PMID:28560402

A user's guide to cannabinoid therapies in oncology.
Maida V, Daeninck PJ.
Curr Oncol. 2016 Dec;23(6):398-406. doi: 10.3747/co.23.3487. Epub 2016 Dec 21. Review.
PMID:28050136

Free PMC Article Quantitative Analyses of Synergistic Responses between Cannabidiol and DNA-Damaging Agents on the Proliferation and Viability of Glioblastoma and Neural Progenitor Cells in Culture.
Deng L, Ng L, Ozawa T, Stella N.
J Pharmacol Exp Ther. 2017 Jan;360(1):215-224. doi: 10.1124/jpet.116.236968. Epub 2016 Nov 7.
PMID:27821713

Free PMC Article Cannabinoids synergize with carfilzomib, reducing multiple myeloma cells viability and migration.
Nabissi M, Morelli MB, Offidani M, Amantini C, Gentili S, Soriani A, Cardinali C, Leoni P, Santoni G.
Oncotarget. 2016 Nov 22;7(47):77543-77557. doi: 10.18632/oncotarget.12721.
PMID:27769052

Free PMC Article Phyto-, endo- and synthetic cannabinoids: promising chemotherapeutic agents in the treatment of breast and prostate carcinomas.
Fraguas-Sánchez AI, Fernández-Carballido A, Torres-Suárez AI.
Expert Opin Investig Drugs. 2016 Nov;25(11):1311-1323. Epub 2016 Sep 28. Review.
PMID:27633508

Cannabinoids for Symptom Management and Cancer Therapy: The Evidence.
Davis MP.
J Natl Compr Canc Netw. 2016 Jul;14(7):915-22. Review.
PMID:27407130

The Use of Medical Marijuana in Cancer.
Birdsall SM, Birdsall TC, Tims LA.
Curr Oncol Rep. 2016 Jul;18(7):40. doi: 10.1007/s11912-016-0530-0. Review.
PMID:27215434

In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma.
Fisher T, Golan H, Schiby G, PriChen S, Smoum R, Moshe I, Peshes-Yaloz N, Castiel A, Waldman D, Gallily R, Mechoulam R, Toren A.
Curr Oncol. 2016 Mar;23(2):S15-22. doi: 10.3747/co.23.2893. Epub 2016 Mar 16.
PMID:27022310

Free PMC Article Pharmacokinetics of Cannabis in Cancer Cachexia-Anorexia Syndrome.
Reuter SE, Martin JH.
Clin Pharmacokinet. 2016 Jul;55(7):807-812. doi: 10.1007/s40262-015-0363-2. Review.
PMID:26883879

The neuroprotection of cannabidiol against MPP⁺-induced toxicity in PC12 cells involves trkA receptors, upregulation of axonal and synaptic proteins, neuritogenesis, and might be relevant to Parkinson's disease.
Santos NA, Martins NM, Sisti FM, Fernandes LS, Ferreira RS, Queiroz RH, Santos AC.
Toxicol In Vitro. 2015 Dec 25;30(1 Pt B):231-40. doi: 10.1016/j.tiv.2015.11.004. Epub 2015 Nov 7.
PMID:26556726

Free Article The Antitumor Activity of Plant-Derived Non-Psychoactive Cannabinoids.
McAllister SD, Soroceanu L, Desprez PY.
J Neuroimmune Pharmacol. 2015 Jun;10(2):255-67. doi: 10.1007/s11481-015-9608-y. Epub 2015 Apr 28. Review.
PMID:25916739

Free PMC Article A collagen-binding EGFR single-chain Fv antibody fragment for the targeted cancer therapy.
Liang H, Li X, Chen B, Wang B, Zhao Y, Zhuang Y, Shen H, Zhang Z, Dai J.
J Control Release. 2015 Jul 10;209:101-9. doi: 10.1016/j.jconrel.2015.04.029. Epub 2015 Apr 24.
PMID:25916496

Exploiting cannabinoid-induced cytotoxic autophagy to drive melanoma cell death.
Armstrong JL, Hill DS, McKee CS, Hernandez-Tiedra S, Lorente M, Lopez-Valero I, Eleni Anagnostou M, Babatunde F, Corazzari M, Redfern CPF, Velasco G, Lovat PE.
J Invest Dermatol. 2015 Jun;135(6):1629-1637. doi: 10.1038/jid.2015.45. Epub 2015 Feb 10.
PMID:25674907

Free Article Delta(9) -tetrahydrocannabinol and cannabidiol as potential curative agents for cancer: A critical examination of the preclinical literature.
Fowler CJ.
Clin Pharmacol Ther. 2015 Jun;97(6):587-96. doi: 10.1002/cpt.84. Epub 2015 May 2. Review.
PMID:25669486

Modulation of the tumor microenvironment and inhibition of EGF/EGFR pathway: novel anti-tumor mechanisms of Cannabidiol in breast cancer.
Elbaz M, Nasser MW, Ravi J, Wani NA, Ahirwar DK, Zhao H, Oghumu S, Satoskar AR, Shilo K, Carson WE 3rd, Ganju RK.
Mol Oncol. 2015 Apr;9(4):906-19. doi: 10.1016/j.molonc.2014.12.010. Epub 2015 Jan 19.
PMID:25660577
Free PMC Article

[Potential applications of marijuana and cannabinoids in medicine].
Zdrojewicz Z, Pypno D, Cabała K, Bugaj B, Waracki M.
Pol Merkur Lekarski. 2014 Oct;37(220):248-52. Review. Polish.
PMID:25518584

The combination of cannabidiol and Δ9-tetrahydrocannabinol enhances the anticancer effects of radiation in an orthotopic murine glioma model.
Scott KA, Dalgleish AG, Liu WM.
Mol Cancer Ther. 2014 Dec;13(12):2955-67. doi: 10.1158/1535-7163.MCT-14-0402. Epub 2014 Nov 14.
PMID:25398831

Free Article Cannabinoids increase lung cancer cell lysis by lymphokine-activated killer cells via upregulation of ICAM-1.
Haustein M, Ramer R, Linnebacher M, Manda K, Hinz B.
Biochem Pharmacol. 2014 Nov 15;92(2):312-25. doi: 10.1016/j.bcp.2014.07.014. Epub 2014 Jul 25.
PMID:25069049

Targeting multiple cannabinoid anti-tumour pathways with a resorcinol derivative leads to inhibition of advanced stages of breast cancer.
Murase R, Kawamura R, Singer E, Pakdel A, Sarma P, Judkins J, Elwakeel E, Dayal S, Martinez-Martinez E, Amere M, Gujjar R, Mahadevan A, Desprez PY, McAllister SD.
Br J Pharmacol. 2014 Oct;171(19):4464-77. doi: 10.1111/bph.12803. Epub 2014 Sep 5.
PMID:24910342

Free PMC Article Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol.
Romano B, Borrelli F, Pagano E, Cascio MG, Pertwee RG, Izzo AA.
Phytomedicine. 2014 Apr 15;21(5):631-9. doi: 10.1016/j.phymed.2013.11.006. Epub 2013 Dec 25.
PMID:24373545

The effects of cannabidiol and its synergism with bortezomib in multiple myeloma cell lines. A role for transient receptor potential vanilloid type-2.
Morelli MB, Offidani M, Alesiani F, Discepoli G, Liberati S, Olivieri A, Santoni M, Santoni G, Leoni P, Nabissi M.
Int J Cancer. 2014 Jun 1;134(11):2534-46. doi: 10.1002/ijc.28591. Epub 2013 Dec 2.
PMID:24293211

Free Article Cannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effect.
Solinas M, Massi P, Cinquina V, Valenti M, Bolognini D, Gariboldi M, Monti E, Rubino T, Parolaro D.
PLoS One. 2013 Oct 21;8(10):e76918. doi: 10.1371/journal.pone.0076918. eCollection 2013.
PMID:24204703

Free PMC Article Local delivery of cannabinoid-loaded microparticles inhibits tumor growth in a murine xenograft model of glioblastoma multiforme.
Hernán Pérez de la Ossa D, Lorente M, Gil-Alegre ME, Torres S, García-Taboada E, Aberturas Mdel R, Molpeceres J, Velasco G, Torres-Suárez AI.
PLoS One. 2013;8(1):e54795. doi: 10.1371/journal.pone.0054795. Epub 2013 Jan 22.
PMID:23349970

Free PMC Article An open-label extension study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesics.
Johnson JR, Lossignol D, Burnell-Nugent M, Fallon MT.
J Pain Symptom Manage. 2013 Aug;46(2):207-18. doi: 10.1016/j.jpainsymman.2012.07.014. Epub 2012 Nov 8.
PMID:23141881

Free Article Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration.
Takeda S, Okajima S, Miyoshi H, Yoshida K, Okamoto Y, Okada T, Amamoto T, Watanabe K, Omiecinski CJ, Aramaki H.
Toxicol Lett. 2012 Nov 15;214(3):314-9. doi: 10.1016/j.toxlet.2012.08.029. Epub 2012 Sep 8.
PMID:22963825

Free PMC Article Cannabidiol inhibits angiogenesis by multiple mechanisms.
Solinas M, Massi P, Cantelmo AR, Cattaneo MG, Cammarota R, Bartolini D, Cinquina V, Valenti M, Vicentini LM, Noonan DM, Albini A, Parolaro D.
Br J Pharmacol. 2012 Nov;167(6):1218-31. doi: 10.1111/j.1476-5381.2012.02050.x.
PMID:22624859

Free PMC Article Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms.
De Petrocellis L, Ligresti A, Schiano Moriello A, Iappelli M, Verde R, Stott CG, Cristino L, Orlando P, Di Marzo V.
Br J Pharmacol. 2013 Jan;168(1):79-102. doi: 10.1111/j.1476-5381.2012.02027.x.
PMID:22594963

Free PMC Article Cannabidiol as potential anticancer drug.
Massi P, Solinas M, Cinquina V, Parolaro D.
Br J Clin Pharmacol. 2013 Feb;75(2):303-12. doi: 10.1111/j.1365-2125.2012.04298.x. Review.
PMID:22506672

Free PMC Article Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.
Ramer R, Bublitz K, Freimuth N, Merkord J, Rohde H, Haustein M, Borchert P, Schmuhl E, Linnebacher M, Hinz B.
FASEB J. 2012 Apr;26(4):1535-48. doi: 10.1096/fj.11-198184. Epub 2011 Dec 23.
PMID:22198381

Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent.
Sreevalsan S, Joseph S, Jutooru I, Chadalapaka G, Safe SH.
Anticancer Res. 2011 Nov;31(11):3799-807.
PMID:22110202

Free PMC Article Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy.
Shrivastava A, Kuzontkoski PM, Groopman JE, Prasad A.
Mol Cancer Ther. 2011 Jul;10(7):1161-72. doi: 10.1158/1535-7163.MCT-10-1100. Epub 2011 May 12.
PMID:21566064

Free Article A combined preclinical therapy of cannabinoids and temozolomide against glioma.
Torres S, Lorente M, Rodríguez-Fornés F, Hernández-Tiedra S, Salazar M, García-Taboada E, Barcia J, Guzmán M, Velasco G.
Mol Cancer Ther. 2011 Jan;10(1):90-103. doi: 10.1158/1535-7163.MCT-10-0688.
PMID:21220494

Free Article Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis.
McAllister SD, Murase R, Christian RT, Lau D, Zielinski AJ, Allison J, Almanza C, Pakdel A, Lee J, Limbad C, Liu Y, Debs RJ, Moore DH, Desprez PY.
Breast Cancer Res Treat. 2011 Aug;129(1):37-47. doi: 10.1007/s10549-010-1177-4. Epub 2010 Sep 22. Erratum in: Breast Cancer Res Treat. 2012 May;133(1):401-4.
PMID:20859676

Free PMC Article Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain.
Johnson JR, Burnell-Nugent M, Lossignol D, Ganae-Motan ED, Potts R, Fallon MT.
J Pain Symptom Manage. 2010 Feb;39(2):167-79. doi: 10.1016/j.jpainsymman.2009.06.008. Epub 2009 Nov 5.
PMID:19896326

Free Article Pancreaticobiliary fistula evident after ESWL treatment of pancreatolithiasis.
Arakura N, Ozaki Y, Maruyama M, Chou Y, Kodama R, Takayama M, Hamano H, Tanaka E, Kawa S.
Intern Med. 2009;48(7):545-9. Epub 2009 Apr 1.
PMID:19336956

Free Article Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells. McAllister SD, Christian RT, Horowitz MP, Garcia A, Desprez PY.
Mol Cancer Ther. 2007 Nov;6(11):2921-7.
PMID:18025276

Free Article Cannabidiol--recent advances.
Mechoulam R, Peters M, Murillo-Rodriguez E, Hanus LO.
Chem Biodivers. 2007 Aug;4(8):1678-92. Review.
PMID:17712814

The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells.
Massi P, Vaccani A, Bianchessi S, Costa B, Macchi P, Parolaro D.
Cell Mol Life Sci. 2006 Sep;63(17):2057-66.
PMID:16909207

A tale of two cannabinoids: the therapeutic rationale for combining tetrahydrocannabinol and cannabidiol.
Russo E, Guy GW.
Med Hypotheses. 2006;66(2):234-46. Epub 2005 Oct 4.
PMID:16209908

Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines.
Massi P, Vaccani A, Ceruti S, Colombo A, Abbracchio MP, Parolaro D.
J Pharmacol Exp Ther. 2004 Mar;308(3):838-45. Epub 2003 Nov 14.
PMID:14617682

Cancer cachexia and cannabinoids.
Gorter RW.
Forsch Komplementarmed. 1999 Oct;6 Suppl 3:21-2. Review.
PMID:10575285

Antineoplastic activity of cannabinoids.
Munson AE, Harris LS, Friedman MA, Dewey WL, Carchman RA.
J Natl Cancer Inst. 1975 Sep;55(3):597-602.
PMID:1159836