CBD AND HEART DISEASE

Neuropsychiatric and General Interactions of Natural and Synthetic Cannabinoids with Drugs of Abuse and Medicines.
Arellano AL, Papaseit E, Romaguera A, Torrens M, Farré M.
CNS Neurol Disord Drug Targets. 2017;16(5):554-566. doi: 10.2174/1871527316666170413104516. Review.
PMID:28412920

Cannabidiol Protects against Doxorubicin-Induced Cardiomyopathy by Modulating Mitochondrial Function and Biogenesis.
Hao E, Mukhopadhyay P, Cao Z, Erdélyi K, Holovac E, Liaudet L, Lee WS, Haskó G, Mechoulam R, Pacher P.
Mol Med. 2015 Jan 6;21:38-45. doi: 10.2119/molmed.2014.00261.
PMID:25569804

Free PMC Article The effect of cannabidiol on ischemia/reperfusion-induced ventricular arrhythmias: the role of adenosine A1 receptors.
Gonca E, Darıcı F.
J Cardiovasc Pharmacol Ther. 2015 Jan;20(1):76-83. doi: 10.1177/1074248414532013. Epub 2014 May 22.
PMID:24853683

Is the cardiovascular system a therapeutic target for cannabidiol?
Stanley CP, Hind WH, O'Sullivan SE.
Br J Clin Pharmacol. 2013 Feb;75(2):313-22. doi: 10.1111/j.1365-2125.2012.04351.x. Review.
PMID:22670794

Free PMC Article Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy.
Rajesh M, Mukhopadhyay P, Bátkai S, Patel V, Saito K, Matsumoto S, Kashiwaya Y, Horváth B, Mukhopadhyay B, Becker L, Haskó G, Liaudet L, Wink DA, Veves A, Mechoulam R, Pacher P.
J Am Coll Cardiol. 2010 Dec 14;56(25):2115-25. doi: 10.1016/j.jacc.2010.07.033.
PMID:21144973

Free PMC Article Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion.
Walsh SK, Hepburn CY, Kane KA, Wainwright CL.
Br J Pharmacol. 2010 Jul;160(5):1234-42. doi: 10.1111/j.1476-5381.2010.00755.x.
PMID:20590615

Free PMC Article Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture.
Cassol OJ Jr, Comim CM, Silva BR, Hermani FV, Constantino LS, Felisberto F, Petronilho F, Hallak JE, De Martinis BS, Zuardi AW, Crippa JA, Quevedo J, Dal-Pizzol F.
Brain Res. 2010 Aug 12;1348:128-38. doi: 10.1016/j.brainres.2010.06.023. Epub 2010 Jun 16.
PMID:20561509

Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury.
Durst R, Danenberg H, Gallily R, Mechoulam R, Meir K, Grad E, Beeri R, Pugatsch T, Tarsish E, Lotan C.
Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3602-7. Epub 2007 Sep 21.
PMID:17890433

Free Article Effects and interactions of natural cannabinoids on the isolated heart.
Nahas G, Trouve R.
Proc Soc Exp Biol Med. 1985 Nov;180(2):312-6.
PMID:4048169